Scientific Papers

Publications for the 1st quarter of 2010:

Amemiya CT, Powers TP, Prohaska SJ, Grimwood J, Schmutz J, Dickson M, Miyake T, Schoenborn MA, Myers RM, Ruddle FH, and Stadler PF. Complete HOX cluster characterization of the coelacanth provides further evidence for slow evolution of its genome Proc. Natl. Acad. Sci. U. S. A 107: 3622-3627, 2010

Arnold SA, Rivera LB, Miller AF, Carbon JG, Dineen SP, Xie Y, Castrillon DH, Sage EH, Puolakkainen P, Bradshaw AD, and Brekken RA. Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma Dis. Model. Mech. 3:57-72, 2010

Cárdenas V, Thornton JD, Wong KA, Spigner C, and Allen MD. Effects of classroom education on knowledge and attitudes regarding organ donation in ethnically diverse urban high schools. Clin Transplant. Jan 19. [Epub ahead of print] 2010

Cardoso LE, Little PJ, Ballinger ML, Chan CK, Braun KR, Potter-Perigo S, Bornfeldt KE, Kinsella MG, and Wight TN. Platelet-derived growth factor differentially regulates the expression and post-translational modification of versican by arterial smooth muscle cells through distinct protein kinase C and extracellular signal-regulated kinase pathways J. Biol. Chem. 2009

Chung IM, Kim JM, Pak YK, Jang Y, Yang WI, Han I, Park SJ, Park SW, Huh J, Wight TN, and Ueno H. Blockade of TGF-beta by catheter-based local intravascular gene delivery does not alter the in-stent neointimal response, but enhances inflammation in pig coronary arteries Int. J. Cardiol. 2010

Comeau MR and Ziegler SF. The influence of TSLP on the allergic response Mucosal. Immunol. 3:138-147, 2010

Damodarasamy M, Vernon RB, Karres N, Chang CH, Bianchi-Frias D, Nelson PS, and Reed MJ. Collagen Extracts Derived From Young and Aged Mice Demonstrate Different Structural Properties and Cellular Effects in Three-Dimensional Gels J. Gerontol. A Biol. Sci. Med. Sci. 2010

Dever JB, Mallory MA, Mallory JE, Wallace D, and Kowdley KV. Phenotypic Characteristics and Diagnoses of Patients Referred to an Iron Overload Clinic Dig. Dis. Sci. 2009

Durinovic-Bello I, Wu RP, Gersuk VH, Sanda S, Shilling HG, and Nepom GT. Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin Genes Immun. 2010

Faner R, James EA, Huston L, Pujol-Borrel R, Kwok WW, and Juan M. Reassessing the role of HLA-DRB3 T-cell responses: evidence for significant expression and complementary antigen presentation Eur. J. Immunol. 40:91-102, 2010

Fischer N, Haug M, Kwok WW, Kalbacher H, Wernet D, Dannecker GE, and Holzer U. Involvement of CD91 and scavenger receptors in Hsp70-facilitated activation of human antigen-specific CD4(+) memory T cells Eur. J. Immunol. 2010

Flack SH and Bernards CM. Cerebrospinal fluid and spinal cord distribution of hyperbaric bupivacaine and baclofen during slow intrathecal infusion in pigs Anesthesiology 112:165-173, 2010

Ge X, Tan V, Bollyky PL, Standifer NE, James EA, and Kwok WW. Assessment Of Seasonal Influenza A Specific CD4 T Cell Responses To 2009 Pandemic H1N1 Swine-Origin Influenza A Virus J. Virol. 2010

Gottlieb PA, Quinlan S, Krause-Steinrauf H, Greenbaum CJ, Wilson DM, Rodriguez H, Schatz DA, Moran AM, Lachin JM, and Skyler JS. Failure to Preserve beta-cell function with Mycophenolate Mofetil and Daclizumab Combined Therapy in patients with new onset Type 1 Diabetes Diabetes Care 2010

Han CY, Kargi AY, Omer M, Chan CK, Wabitsch M, O'Brien KD, Wight TN, and Chait A. Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation Diabetes 59:386-396, 2010

Honeyman MC, Stone NL, Falk BA, Nepom GT, and Harrison LC.  Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens.  J Immunol 184(4):2204-10, 2010

Hulse KE, Reefer AJ, Engelhard VH, Patrie JT, Ziegler SF, Chapman MD, and Woodfolk JA. Targeting allergen to FcgammaRI reveals a novel T(H)2 regulatory pathway linked to thymic stromal lymphopoietin receptor J. Allergy Clin. Immunol. 125:247-256, 2010

Jager A, Dardalhon V, Sobel RA, Bettelli E, and Kuchroo VK. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes J. Immunol. 183:7169-7177, 2009

Kim YJ, Fan Y, Laurie P, 'hugo' Kim JM, and Ravits J. No evidence of HIV pol gene in spinal cord tissues in sporadic ALS by real-time RT-PCR Amyotroph. Lateral. Scler. 1-9, 2009

Kowdley KV. The Role of Iron in Nonalcoholic Fatty Liver Disease: The Story Continues Gastroenterology 2010

Lin OS, Kozarek RA, Arai A, Gan SI, Gluck M, Jiranek GC, Kowdley KV, and Triadafilopoulos G. The association between cholecystectomy and gastroesophageal reflux symptoms: a prospective controlled study Ann. Surg. 251:40-45, 2010

Long SA, Cerosaletti K, Bollyky PL, Tatum M, Shilling H, Zhang S, Zhang ZY, Pihoker C, Sanda S, Greenbaum CJ, and Buckner JH. Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects Diabetes 59:407-415, 2010

Messner DJ and Kowdley KV. Biting the iron bullet: endoplasmic reticulum stress adds the pain of hepcidin to chronic liver disease Hepatology 51:705-707, 2010

Nelson JE and Kowdley KV. IkappaB kinase epsilon: a potential therapeutic target for obesity (and nonalcoholic fatty liver disease)? Hepatology 51:336-338, 2010

Orban T, Farkas K, Jalahej H, Kis J, Treszl A, Falk B, Reijonen H, Wolfsdorf J, Ricker A, Matthews JB, Tchao N, Sayre P, and Bianchine P. Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy J. Autoimmun. 2009

Pescovitz MD, Greenbaum CJ, Krause-Steinrauf H, Becker DJ, Gitelman SE, Goland R, Gottlieb PA, Marks JB, McGee PF, Moran AM, Raskin P, Rodriguez H, Schatz DA, Wherrett D, Wilson DM, Lachin JM, and Skyler JS. Rituximab, B-lymphocyte depletion, and preservation of beta-cell function N. Engl. J. Med. 361:2143-2152, 2009

Price L and Kowdley KV. The role of iron in the pathophysiology and treatment of chronic hepatitis C Can. J. Gastroenterol. 23:822-828, 2009

Rabin SJ, Kim JM, Baughn M, Libby RT, Kim YJ, Fan Y, Libby RT, La Spada A, Stone BC, and Ravits J. Sporadic ALS has compartment-specific aberrant exon splicing and altered cell-matrix adhesion biology Hum. Mol. Genet. 19:313-328, 2010

Saha NR, Smith J, and Amemiya CT. Evolution of adaptive immune recognition in jawless vertebrates Semin. Immunol. 22: 25-33, 2010

Seet L-F, Su R, Barathi VA, Lee WS, Poh R, Heng YM, Vithana EN, Aung T, Weaver MS, Sage EH, and Wong TT. SPARC Deficiency Results in Improved Surgical Survival in a Novel Mouse Model of Glaucoma Filtration Surgery, PLOS One  Feb. 25 (Epub ahead of print)

Shukla S, Nair R, Rolle MW, Braun KR, Chan CK, Johnson PY, Wight TN, and McDevitt TC. Synthesis and Organization of Hyaluronan and Versican by Embryonic Stem Cells Undergoing Embryoid Body Differentiation J. Histochem. Cytochem. 2009

Song Q, Han Q, Bradshaw EM, Kent SC, Raddassi K, Nilsson B, Nepom GT, Hafler DA, and Love JC. On-chip activation and subsequent detection of individual antigen-specific T cells Anal. Chem. 82:473-477, 2010

Tanino Y, Coombe DR, Gill SE, Kett WC, Kajikawa O, Proudfoot AE, Wells TN, Parks WC, Wight TN, Martin TR, and Frevert CW. Kinetics of Chemokine-Glycosaminoglycan Interactions Control Neutrophil Migration into the Airspaces of the Lungs J. Immunol. 2010

Treeprasertsuk S, Kowdley KV, Luketic VA, Harrison ME, McCashland T, Befeler AS, Harnois D, Jorgensen R, Petz J, Keach J, Schmoll J, Hoskin T, Thapa P, Enders F, and Lindor KD. The predictors of the presence of varices in patients with primary sclerosing cholangitis Hepatology 2009

Utzschneider KM and Kowdley KV. Hereditary hemochromatosis and diabetes mellitus: implications for clinical practice Nat. Rev. Endocrinol. 6:26-33, 2010

Vendrame F, Pileggi A, Laughlin E, Allende G, Martin-Pagola A, Molano RD, Diamantopoulos S, Standifer N, Geubtner K, Falk BA, Ichii H, Takahashi H, Snowhite I, Chen Z, Mendez A, Chen L, Sageshima J, Ruiz P, Ciancio G, Ricordi C, Reijonen H, Nepom GT, Burke GW III, and Pugliese A. Recurrence of Type 1 Diabetes after Simultaneous Pancreas-Kidney Transplantation, despite Immunosuppression, Associated with Autoantibodies and Pathogenic Autoreactive CD4 T-cells Diabetes 2010

Weaver MS, Workman G, Cardo-Vila M, Arap W, Pasqualini R, and Sage EH. Processing of the matricellular protein Hevin in mouse brain is dependent on ADAMTS4 J. Biol. Chem. 2009