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Study Title: Randomized Study comparing Human Corticotropin-Releasing Factor to Placebo for Patients Requiring High-dose Dexamethasone
Category: Cancer, General

Currently accepting participants?
Not at this time.

Principal Investigator: Lynne Taylor MD
Study Coordinator: Jill Zeller RN
Phone: 206-223-6835
Email: jill.zeller@vmmc.org

What is the Randomized Study comparing Human Corticotropin-Releasing Factor to Placebo for Patients Requiring High-dose Dexamethasone study?

Patients in both groups will have brain tumors that are causing swelling in the brain and are taking Decadron to control their symptoms. One group of people will receive XERECEPT®. The other group of people will receive a placebo.

Who can participate?

Subjects must be 18 years or older and require the administration of at lest 4mg of Dexamethasone per day for control of brain edema symptoms.

What do I have to do as a study participant?

Study Summary:

The purpose of this study is to examine
the safety and efficacy of XERECEPT®
compared to Decadron® for patients
who require long-term high doses of
Decadron to control the symptoms of
brain swelling (edema).

Detailed Study Description:

(No information)

Study Design: Blinded
Phase of Study: Phase III
Study Type: Interventional
Condition or Study Focus: Peritumoral Brain Edema
Intervention Type: Drug
Intervention Name: Xerecept: Human Corticotropin-Releasing Factor (hCRF)
Gender: Male and Female
Age group: Interventional
Sponsor: Celtic Pharma

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